2017
The TNQ Distinguished Lectures in the Life Sciences Series I. 7th Edition.

Mary-Claire King

'Understanding Inherited Breast and Ovarian Cancer: From Gene Discovery to Precision Medicine and Public Health'
Chennai | Bengaluru | New Delhi | Kolkata

University of Washington geneticist Dr Mary-Claire King who pioneered the idea that breast cancer could be a heritable disease, gave free lectures in the Seventh Annual Cell Press-TNQ India Distinguished Lectureship Series

Dr Mary-Claire King gave free lectures in Bengaluru, Chennai, Delhi and Kolkata in February 2017. She was the Featured Speaker of the Seventh Annual Cell Press-TNQ India Distinguished Lectureship Series, aimed at bringing internationally renowned scientists to the Indian scientific community.

Professor King may be best known for demonstrating that breast and ovarian cancer can be inherited genetically rather than occurring only by chance or from environmental influences. She and her colleagues pinpointed a gene, BRCA1, which carries mutations that dramatically increase a woman’s risk of developing breast or ovarian cancer during her lifetime.

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Professor King’s work also crosses into matters of human rights. By pioneering methods of extracting and sequencing maternally inherited mitochondrial DNA, she made it possible for more than 100 children who ‘disappeared’ during the Argentinian military dictatorship to be reunited with their families. The approaches she developed are now in routine use in forensic science.

Another seminal contribution from Dr King’s research was the insight that despite dramatic differences in appearance, humans and chimpanzees share 99% of their genetic code, paving the way for greater understanding of how genomes change during evolution and the relationships of humans to other primates.

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In addition to her work on inherited breast and ovarian cancer, Dr King is currently studying the genetic bases of schizophrenia and of severe pediatric disorders. She is the American Cancer Society Professor of Medicine and Genome Sciences at the University of Washington. She graduated cum laude with a degree in mathematics from Carleton College, completed her PhD in genetics at the University of California, Berkeley and was a postdoc at the University of California, San Francisco.

She was professor of genetics at the University of California, Berkeley from 1975 until 1995. She has led her lab at the University of Washington since 1995, and in 2012, was elected as the President of the American Society of Human Genetics.

Awards &
Honors

1994

American Association for Cancer Research, Clowes Award for Basic Research

2004

Peter and Patricia Gruber Foundation, Genetics Prize

2005

Elected to the National Academy of Sciences of the U.S.A.

2006

Weizmann Institute, Award for Women & Science

2006

American Cancer Society, Medal of Honor for Clinical Research

2006

Royal Netherlands Academy of Arts and Sciences, Dr A.H. Heineken Prize for Medicine

2009

Elected to the French Academy of Sciences (foreign member)

2010

CSHL Double Helix Medal Honoree

2011

The Rockefeller University, Pearl Meister Greengard Prize

2012

Elected to the American Philosophical Society

2013

Paul Ehrlich and Ludwig Darmstaedter Prize

2014

Lasker-Koshland Award for Special Achievement in Medical Science

2016

United States National Medal of Science

Lecture Schedule

LOCATION

Chennai:

Sir Mutha Venkatasubba Rao (Lady Andal) Concert Hall, Chetpet

DATE

February 20, 2017. 6.00 p.m.

Bengaluru:

JN Tata Auditorium (IISc.)

February 22, 2017. 4.30 p.m.

New Delhi:

Jawaharlal Auditorium, All India Institute of Medical Sciences(AIIMS)

February 24, 2017. 4.30 p.m.

Kolkata:

Kala Mandir Hall, Shakespeare Sarani

February 28, 2017. 11.00 a.m

Lecture Schedule

LOCATION

Chennai:​

Sir Mutha Venkatasubba Rao (Lady Andal) Concert Hall, Chetpet

DATE

February 20, 2017. 6.00 p.m.

LOCATION

Bengaluru:

JN Tata Auditorium (IISc.)

DATE

February 22, 2017. 4.30 p.m.

LOCATION

New Delhi:

Jawaharlal Auditorium, All India Institute of Medical Sciences(AIIMS)

DATE

February 24, 2017. 4.30 p.m.

LOCATION

Kolkata:

Kala Mandir Hall, Shakespeare Sarani

DATE

February 28, 2017. 11.00 a.m

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